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The prevalence of chronic airway disease is estimated to be 14 to 80 percent in individual horse populations throughout the United States and Europe, accounting for respiratory disease as the second cause of retirement in horses. Recurrent airway obstruction (RAO), an asthma-like disease, has been cited as one of the most frequent respiratory diseases in horses. Intravenous administration of magnesium sulfate solution is used to treat acute asthma attacks in people. Researchers will determine whether magnesium sulfate therapy can relax airway smooth muscle and improve ventilation in horses that experience seasonal RAO. This study will provide new information on the safety and efficacy of this novel and inexpensive therapy for managing horses with acute respiratory distress.

Study ID
D15EQ-803
Study Status
Complete
Start Date
05/01/2015
Grant amount awarded
$10,800
Grant recipient
Mississippi State University Research & Technology Corporation
Study country
United States
Investigator
Jacquelyn E. Bowser, DVM
Study category
Respiratory