Identifying Genetic and Behavioral Factors Influencing Weight Gain

Almost 60% of dogs are considered overweight. Researchers will look for factors other than diet that drive overeating in dogs, including genetics. The team has mapped genomic factors associated with obesity in Labrador retrievers and validated genes contributing to obesity risk in this breed. Using client-owned Labrador retrievers as a model, the team will compare eating behavior and energy expenditure in high obesity-risk to low obesity-risk dogs to identify additional factors that drive weight gain. Researchers also will analyze data from owners to identify owner behaviors that may influence weight in both low-risk and high-risk dogs. Findings will be used to inform clinical trials to improve obesity prevention and treatment.